Scientists manufacture living blood vessel2022-10-28
An international consortium of researchers led by the University of Sydney, has developed technology to enable the manufacturing of materials that mimic the structure of living blood vessels, with significant implications for the future of surgery.
Preclinical testing found that following transplantation of the manufactured blood vessel into mice, the body accepted the material, with new cells and tissue growing in the right places — in essence transforming it into a ‘living blood vessel.’
Senior author Professor Anthony Weiss from the Charles Perkins Centre said while others have tried to build blood vessels with various degrees of success before, this is the first time scientists have seen the vessels develop with such a high degree of similarity to the complex structure of naturally occurring blood vessels.
“Nature converts this manufactured tube over time to one that looks, behaves and functions like a real blood vessel,” said Professor Weiss.
“The technology’s ability to recreate the complex structure of biological tissues shows it has the potential to not only manufacture blood vessels to assist in surgery, but also sets the scene for the future creation of other synthetic tissues such as heart valves.”
Co-author Dr Christopher Breuer of the Center for Regenerative Medicine at Nationwide Children’s Hospital and the Wexner Medical Center in Columbus, USA said he is excited about the potential of the research for children.
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